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1

NAD+ and sirtuins in aging and disease

Imai, Shin-ichiro, Guarente, Leonard

Journal:

Trends in Cell Biology

Année:

2014

Langue:

english

Fichier:

PDF, 617 KB

english, 2014

2

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

Yoshino, Jun, Baur, Joseph A., Imai, Shin-ichiro

Journal:

Cell Metabolism

Année:

2017

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2017

3

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

de Picciotto, Natalie E., Gano, Lindsey B., Johnson, Lawrence C., Martens, Christopher R., Sindler, Amy L., Mills, Kathryn F., Imai, Shin-ichiro, Seals, Douglas R.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 666 KB

english, 2016

4

It takes two to tango: NAD+ and sirtuins in aging/longevity control

Imai, Shin-ichiro, Guarente, Leonard

Journal:

npj Aging and Mechanisms of Disease

Année:

2016

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2016

5

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

Jun Yoshino, Kathryn F. Mills, Myeong Jin Yoon, Shin-ichiro Imai

Journal:

Cell Metabolism

Année:

2011

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2011

6

The brain, sirtuins, and ageing

Satoh, Akiko, Imai, Shin-ichiro, Guarente, Leonard

Journal:

Nature Reviews Neuroscience

Année:

2017

Langue:

english

Fichier:

PDF, 663 KB

english, 2017

7

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

Imai, Shin-ichiro

Journal:

npj Systems Biology and Applications

Année:

2016

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2016

8

“Clocks” in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging

Shin-ichiro Imai

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2010

Langue:

english

Fichier:

PDF, 414 KB

english, 2010

9

The two-process model of cellular aging

Hiroaki Kitano, Shin-ichiro Imai

Journal:

Experimental Gerontology

Année:

1998

Langue:

english

Fichier:

PDF, 540 KB

english, 1998

10

A Clock Ticks in Pancreatic β Cells

Jun Yoshino, Shin-ichiro Imai

Journal:

Cell Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 128 KB

english, 2010

11

Mitochondrial SIRT3: A New Potential Therapeutic Target for Metabolic Syndrome

Jun Yoshino, Shin-ichiro Imai

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 136 KB

english, 2011

12

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Shin-ichiro Imai, Leonard Guarente

Journal:

Trends in Pharmacological Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 351 KB

english, 2010

13

Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH

Satoh, Akiko, Brace, Cynthia S., Rensing, Nick, Cliften, Paul, Wozniak, David F., Herzog, Erik D., Yamada, Kelvin A., Imai, Shin-ichiro

Journal:

Cell Metabolism

Année:

2013

Langue:

english

Fichier:

PDF, 3.76 MB

english, 2013

14

Systemic regulation of mammalian ageing and longevity by brain sirtuins

Satoh, Akiko, Imai, Shin-ichiro

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 394 KB

english, 2014

15

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

Imai, Shin-ichiro

Journal:

Frontiers in Bioscience

Année:

2009

Langue:

english

Fichier:

PDF, 374 KB

english, 2009

16

Slc12a8 is a nicotinamide mononucleotide transporter

Grozio, Alessia, Mills, Kathryn F., Yoshino, Jun, Bruzzone, Santina, Sociali, Giovanna, Tokizane, Kyohei, Lei, Hanyue Cecilia, Cunningham, Richard, Sasaki, Yo, Migaud, Marie E., Imai, Shin-ichiro

Journal:

Nature Metabolism

Année:

2019

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2019

17

Viscoelastic Behavior of Surfactant Threadlike Micellar Solutions: Effect of Additives 3

Shin-ichiro Imai, Toshiyuki Shikata

Journal:

Journal of Colloid and Interface Science

Année:

2001

Langue:

english

Fichier:

PDF, 93 KB

english, 2001

18

The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance

Shin-ichiro Imai

Journal:

Cell Biochemistry and Biophysics

Année:

2009

Langue:

english

Fichier:

PDF, 395 KB

english, 2009

19

Simultaneous determination of zonisamide, carbamazepine and carbamazepine-10,11-epoxide in infant serum by high-performance liquid chromatography

Terumitsu Yoshida, Koichi Imai, Sumiko Motohashi, Shin-ichiro Hamano, Masato Sato

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2006

Langue:

english

Fichier:

PDF, 214 KB

english, 2006

20

Preparation of polyimide Langmuir-Blodgett films possessing a triphenylamine unit and their application to photodiodes

Yasunari Nishikata, Shin-ichiro Fukui, Masa-aki Kakimoto, Yoshio Imai, Katsuhiko Nishiyama, Masamichi Fujihira

Journal:

Thin Solid Films

Année:

1992

Langue:

english

Fichier:

PDF, 221 KB

english, 1992

21

Transcortical sensory aphasia following the unilateral left thalamic infarction— A case report

Maeshima, Shin-ichiro, Komai, Norihiko, Kinoshita, Yasunobu, Ueno, Masami, Nakai, Ekini, Naka, Yutaka, Tsuji, Naoki, Imai, Harumichi, Kido, Takuhei

Journal:

Journal of Neurolinguistics

Année:

1992

Langue:

english

Fichier:

PDF, 1.67 MB

english, 1992

22

Effects of selective logging on tree species diversity and composition of Bornean tropical rain forests at different spatial scales

Nobuo Imai, Tatsuyuki Seino, Shin-ichiro Aiba, Masaaki Takyu, Jupiri Titin and Kanehiro Kitayama

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2012

23

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Mills, Kathryn F., Yoshida, Shohei, Stein, Liana R., Grozio, Alessia, Kubota, Shunsuke, Sasaki, Yo, Redpath, Philip, Migaud, Marie E., Apte, Rajendra S., Uchida, Koji, Yoshino, Jun, Imai, Shin-ichiro

Journal:

Cell Metabolism

Année:

2016

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2016

24

The Development of Three-Dimensional Aerodynamic Design Blades for Turbines.

TANUMA, Tadashi, NAGAO, Shin-ichiro, SAKAMOTO, Taro, IKEDA, Nobukazu, MATSUDA, Minoru, IMAI, Ken-ichi

Journal:

JSME International Journal Series B

Année:

1998

Fichier:

PDF, 2.11 MB

1998

25

The Pathophysiological Significance of NAD+ in the Regulation of Metabolism in Mammals and Its Therapeutic Potential

YOSHINO, Jun, IMAI, Shin-ichiro

Journal:

KAGAKU TO SEIBUTSU

Année:

2013

Fichier:

PDF, 1.01 MB

2013

26

A simple method for the quantification of famotidine in human plasma and urine by paired-ion high performance liquid chromatography

Yasuhiko Imai, Shin-Ichiro Kobayashi

Journal:

Biomedical Chromatography

Année:

1992

Langue:

english

Fichier:

PDF, 212 KB

english, 1992

27

ChemInform Abstract: Structure, Magnetism, and Ionic Conductivity of the Gigantic {Mo176}-Wheel Assembly: Na15Fe3Co16 [Mo176O528H3(H2O)80] Cl27·450H2O.

Hiroyuki Imai, Tomoyuki Akutagawa, Fumito Kudo, Mitsuhiro Ito, Kazuhiro Toyoda, Shin-ichiro Noro, Leroy Cronin, Takayoshi Nakamura

Journal:

Année:

2009

Fichier:

PDF, 18 KB

2009

28

Application of high-performance liquid chromatography with a chemiluminescence detection system to determine catecholamines in urine

Shin-Ichiro Kobayashi, Jun Sekino, Kazumasa Honda, Kazuhiro Imai

Journal:

Analytical Biochemistry

Année:

1981

Langue:

english

Fichier:

PDF, 443 KB

english, 1981

29

Effect of backbone structures of polysilanes on the photooxidation reaction

Keiji Kabeta, Kiyoaki Shuto, Shin-ichiro Sugi, Takafumi Imai

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 588 KB

english, 1996

30

Effect of Carbon Ion Radiotherapy for Sacral Chordoma: Results of Phase I-II and Phase II Clinical Trials

Reiko Imai, Tadashi Kamada, Hiroshi Tsuji, Shinji Sugawara, Itsuko Serizawa, Hirohiko Tsujii, Shin-ichiro Tatezaki

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2010

Langue:

english

Fichier:

PDF, 396 KB

english, 2010

31

Viscoelastic behavior of surfactant threadlike micellar solutions: effects of additives, 4

Toshiyuki Shikata, Mamoru Shiokawa, Shin-ichiro Imai

Journal:

Journal of Colloid and Interface Science

Année:

2003

Langue:

english

Fichier:

PDF, 415 KB

english, 2003

32

Longer transplanted heart allograft survival in rats without immunosuppressants after intrathymic myocardial cell inoculation in the neonatal period

Kazuhiro Seo, Shin-ichiro Imamura, Yoshiko Ohta, Toshio Nishikawa, Yasuharu Imai

Journal:

Heart and Vessels

Année:

1993

Langue:

english

Fichier:

PDF, 507 KB

english, 1993

33

Discovery and characterization ofd-phenylserine deaminase fromArthrobactersp. TKS1

Hisashi Muramatsu, Yuri Suzuki, Takeshi Imai, Sakuko Ueshima, Jun Ozaki, Yuji Matsui, Shin-ichiro Kato, Kouhei Ohnishi, Norihiro Kimoto, Hiroaki Yamamoto, Shinji Nagata

Journal:

Applied Microbiology and Biotechnology

Année:

2011

Langue:

english

Fichier:

PDF, 750 KB

english, 2011

34

Extractives ofQuercus crispulasapwood infected by the pathogenic fungiRaffaelea quercivoraI: comparison of sapwood extractives from noninfected and infected samples

Kayoko Imai, Tohru Mitsunaga, Hiroyuki Takemoto, Toshihiro Yamada, Shin-ichiro Ito, Hideo Ohashi

Journal:

Journal of Wood Science

Année:

2009

Langue:

english

Fichier:

PDF, 474 KB

english, 2009

35

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

Kathryn Moynihan Ramsey, Kathryn F. Mills, Akiko Satoh, Shin-ichiro Imai

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 235 KB

english, 2008

36

Is Sirt1 a miracle bullet for longevity?

Shin-ichiro Imai

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 72 KB

english, 2007

37

A nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expression

Andrew A. Grimm, Cynthia S. Brace, Ting Wang, Gary D. Stormo, Shin-Ichiro Imai

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 593 KB

english, 2011

38

10.1038/35001622

Guarente, Leonard, Imai, Shin-ichiro, Armstrong, Christopher M., Kaeberlein, Matt

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 503 KB

english, 2000

39

Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis

Imai, Nozomi, Hashimoto, Tatsuo, Kihara, Minoru, Yoshida, Shin-ichiro, Kawana, Ichiro, Yazawa, Takuya, Kitamura, Hitoshi, Umemura, Satoshi

Journal:

Laboratory Investigation

Année:

2006

Langue:

english

Fichier:

PDF, 414 KB

english, 2006

40

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme

Wang, Tao, Zhang, Xiangbin, Bheda, Poonam, Revollo, Javier R, Imai, Shin-ichiro, Wolberger, Cynthia

Journal:

Nature Structural and Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 296 KB

english, 2006

41

Impact of carbon ion radiotherapy for unresectable osteosarcoma of the trunk

Akira Matsunobu, Reiko Imai, Tadashi Kamada, Takeshi Imaizumi, Hiroshi Tsuji, Hirohiko Tsujii, Yoshiyuki Shioyama, Hiroshi Honda, Shin-ichiro Tatezaki, for the Working Group for Bone, Soft Tissue Sarc

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1022 KB

english, 2012

42

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

Shin-ichiro Imai

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 458 KB

english, 2011

43

DJ-1 associates with synaptic membranes

Yukiko Usami, Taku Hatano, Satoshi Imai, Shin-ichiro Kubo, Shigeto Sato, Shinji Saiki, Yoichiro Fujioka, Yusuke Ohba, Fumiaki Sato, Manabu Funayama, Hiroto Eguchi, Kaori Shiba, Hiroyoshi Ariga, Jie Sh

Journal:

Neurobiology of Disease

Année:

2011

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2011

44

Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene

Noriyuki Yanaka, Jun Kotera, Akio Ohtsuka, Hiroyuki Akatsuka, Yuji Imai, Hideo Michibata, Kotomi Fujishige, Eri Kawai, Shin-Ichiro Takebayashi, Katsuzumi Okumura, Kenji Omori

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 794 KB

english, 1998

45

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase

Uffe H Olesen, Jakob G Petersen, Antje Garten, Wieland Kiess, Jun Yoshino, Shin-Ichiro Imai, Mette K Christensen, Peter Fristrup, Annemette V Thougaard, Fredrik Björkling, Peter B Jensen, Søren J Niel

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 964 KB

english, 2010

46

Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance

Jun Yoshino, Caterina Conte, Luigi Fontana, Bettina Mittendorfer, Shin-ichiro Imai, Kenneth B. Schechtman, Charles Gu, Iris Kunz, Filippo Rossi Fanelli, Bruce W. Patterson, Samuel Klein

Journal:

Cell Metabolism

Année:

2012

Langue:

english

Fichier:

PDF, 547 KB

english, 2012

47

PCCX1, a Novel DNA-Binding Protein with PHD Finger and CXXC Domain, Is Regulated by Proteolysis

Tadahiro Fujino, Mayumi Hasegawa, Shinsuke Shibata, Taishiro Kishimoto, Shin-ichiro Imai, Toshiya Takano

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 233 KB

english, 2000

48

Loss of collagenase gene expression in immortalized clones of SV40 T antigen-transformed human diploid fibroblasts

Shin-ichiro Imai, Toshiya Takano

Journal:

Biochemical and Biophysical Research Communications

Année:

1992

Langue:

english

Fichier:

PDF, 2.14 MB

english, 1992

49

Expression of a MADS box gene, MEF2D, in neurons of the mouse central nervous system: implication of its binary function in myogenic and neurogenic cell lineages

Hiroko Ikeshimaa, Shin-ichiro Imai, Kouji Shimoda, Jun-ichi Hata, Toshiya Takano

Journal:

Neuroscience Letters

Année:

1995

Langue:

english

Fichier:

PDF, 517 KB

english, 1995

50

From heterochromatin islands to the NAD World: A hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis

Shin-ichiro Imai

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2009

Langue:

english

Fichier:

PDF, 543 KB

english, 2009